TABLE 1.
Clinical and pathological features according to the EMT clusters.
| Clinical and pathological factors | EMT C1 | EMT C2 | p-value | |
|---|---|---|---|---|
| Progression status | Progression | 127 | 229 | <0.001* |
| Progression free | 318 | 340 | ||
| Mean (SD) | 67.6 (8.5) | 65.2 (9.9) | ||
| Sex | Female | 115 | 291 | <0.001 |
| Male | 330 | 278 | ||
| Race | Asian | 6 | 10 | 0.784 |
| Black | 31 | 51 | ||
| White | 305 | 431 | ||
| American Indian | — | 1 | ||
| pT stage | T1 | 41 | 75 | 0.005 |
| T1a | 20 | 51 | ||
| T1b | 34 | 61 | ||
| T2 | 155 | 184 | ||
| T2a | 82 | 87 | ||
| T2b | 33 | 28 | ||
| T3 | 61 | 57 | ||
| T4 | 19 | 23 | ||
| TX | — | 3 | ||
| pN stage | N0 | 292 | 357 | 0.001 |
| N1 | 113 | 113 | ||
| N2 | 31 | 83 | ||
| N3 | 4 | 3 | ||
| NX | 5 | 12 | ||
| pM stage | M0 | 356 | 399 | 0.003 |
| M1 | 5 | 18 | ||
| M1a | 1 | 2 | ||
| M1b | 1 | 5 | ||
| MX | 78 | 141 | ||
| pTNM stage | I | 3 | 5 | <0.001 |
| IA | 75 | 145 | ||
| IB | 147 | 143 | ||
| II | 3 | 1 | ||
| IIA | 58 | 57 | ||
| IIB | 82 | 82 | ||
| III | 2 | 1 | ||
| IIIA | 51 | 85 | ||
| IIIB | 15 | 14 | ||
| IV | 7 | 26 | ||
| Metastasis status | Metastasis | 34 | 62 | 0.546 |
| Metastasis: primary | 2 | 1 | ||
| Metastasis: recurrence | 2 | 9 | ||
| Primary | 9 | 14 | ||
| Recurrence | 25 | 52 | ||
| Smoking history | Non-smoking | 14 | 78 | <0.001 |
| Smoking | 421 | 475 | ||
| Radioation history | Non-radiation | 132 | 148 | 0.928 |
| Radiation | 14 | 14 | ||
*p value <0.05 are marked in bold.