Table 1.
Clinical characteristics of study participants.
| C (n=9) | MV (n=25) | SV (n=11) | P value | |
|---|---|---|---|---|
| age (years)# | 61.56 ± 8.59 | 61.2 ± 10.83 | 58.73 ± 11.82 | 0.79 |
| Female& | 4 (44.4) | 9 (36) | 2 (18.2) | 0.42 |
| Smoking history& | 3 (33.3) | 12 (48) | 9 (81.2) | 0.07 |
| Hypertension history& | 4 (44.4) | 13 (52) | 6 (54.5) | 0.90 |
| Diabetes history& | 3 (33.3) | 12 (48) | 3 (27.3) | 0.46 |
| NT-proBNP(pg/ml)# | 759.67 ± 1268.76 | 1490.30 ± 2128.41 | 301.27 ± 649.84 | 0.15 |
| LVEF(%)# | 56.56 ± 10.64 | 61.68 ± 6.01 | 61.91 ± 6.92 | 0.18 |
| LVDd(mm)# | 51.33 ± 6.67 | 47.04 ± 3.98 | 44.09 ± 5.66 | 0.01§ |
| LVDs(mm)# | 34.11 ± 7.75 | 27.79 ± 11.01 | 28.64 ± 4.88 | 0.22 |
| LA(mm)# | 33.56 ± 6.46 | 32.12 ± 4.87 | 29.18 ± 3.03 | 0.12 |
| IVS(mm)# | 10.00 ± 1.50 | 12.12 ± 5.89 | 10.73 ± 1.01 | 0.43 |
| RV(mm)# | 21.22 ± 2.22 | 20.96 ± 1.74 | 20.82 ± 1.47 | 0.88 |
| TC(mmol/L)# | 4.85 ± 1.14 | 5.36 ± 1.42 | 4.43 ± 0.94 | 0.13 |
| TG(mmol/L)α | 0.65 (0.83,1.23) | 1.26 (1.79,2.46) | 1.19 (1.92,3.72) | 0.03*§ |
| HDL(mmol/L)# | 1.34 ± 0.26 | 1.07 ± 0.2 | 1.09 ± 0.17 | 0.01*§ |
| LDL(mmol/L)α | 1.11 (1.28,1.58) | 0.98 (1.06,1.19) | 0.94 (1.13,1.19) | 0.13 |
| BMI(kg/m2)# | 22.84 ± 3.06 | 23.29 ± 3.13 | 24.07 ± 3.5 | 0.68 |
| ALT(U/L)α | 13.45 (19.2,35.9) | 18.45 (24.7,46.6) | 15.9 (27.4,40.3) | 0.34 |
| AST(U/L)α | 18.55 (23.4,31.55) | 20.15 (30.5,87.45) | 16.8 (21.7,26.7) | 0.08 |
| TP(g/L)# | 72.08 ± 7.35 | 69.26 ± 6.23 | 68.48 ± 6.7 | 0.44 |
| ALB(g/L)# | 44.52 ± 2.95 | 42.63 ± 4.15 | 42.66 ± 7.17 | 0.59 |
| TBil(umol/L)# | 13.4 ± 4.2 | 13.26 ± 6.44 | 11.94 ± 2.69 | 0.76 |
| TBA(umol/L)α | 3.15 (5.3,8.8) | 2 (3.6,6.4) | 2.8 (3.9,5.1) | 0.35 |
| UA(umol/L)# | 364.43 ± 108.5 | 356.51 ± 98.34 | 370.92 ± 69.6 | 0.91 |
| Crea(umol/L)# | 65.83 ± 16.12 | 68.74 ± 16.94 | 68.21 ± 11.67 | 0.89 |
| GFR(ml/min)α | 79.35 (102.5,107.1) | 91.25 (98.2,107.35) | 89.1 (103.3,107.6) | 0.96 |
| WBC (10^9/L)α | 4.99 (7.16,7.48) | 7.14 (8.33,10.82) | 5.73 (7.06,7.96) | 0.05 |
| NEU (10^9/L)α | 2.5 (4.16,6.04) | 4.34 (5.74,9.27) | 4.11 (4.43,5.34) | 0.11 |
| LYM (10^9/L)# | 1.62 ± 0.79 | 1.72 ± 0.7 | 1.54 ± 0.38 | 0.73 |
| MONO (10^9/L)α | 0.27 (0.35,0.46) | 0.29 (0.38,0.57) | 0.29 (0.33,0.44) | 0.86 |
| EOS (10^9/L)α | 0.04 (0.15,0.29) | 0.04 (0.12,0.22) | 0.02 (0.06,0.1) | 0.26 |
| BASO (10^9/L)α | 0.01 (0.03,0.04) | 0.02 (0.03,0.05) | 0.01 (0.02,0.03) | 0.17 |
| NEU-R(%)# | 64.36 ± 14.24 | 70.26 ± 12.59 | 71.32 ± 8.56 | 0.38 |
| RBC (10^12/L)# | 4.52 ± 0.44 | 4.44 ± 0.45 | 4.75 ± 0.67 | 0.26 |
| HB (g/L)# | 133.89 ± 12.5 | 135.32 ± 14.56 | 144.45 ± 15.21 | 0.17 |
| HCT# | 0.41 ± 0.03 | 0.41 ± 0.04 | 0.43 ± 0.04 | 0.28 |
| PLT (10^9/L)# | 232 ± 62.18 | 208.76 ± 55.28 | 208.55 ± 71.27 | 0.59 |
| HbA1c (%)α | 4.78 (5.09,7.55) | 5.43 (5.9,7.15) | 5.34(5.64,6.2) | 0.22 |
#mean ± SD,&n (%),αmedian (IQR); Continuous, normally distributed variables among the three groups were analyzed by a one-way analysis of variance. The Kruskal-Wallis H-test was applied for data of this type that were not normally distributed. Continuous, normally distributed variables between two groups were analyzed by Student’s t-test. The Mann Whitney U test was applied for data of this type that were not normally distributed. Categorical variables were compared by the χ2-test. NT-proBNP, N-terminal pro-B type natriuretic peptide; LVEF, left ventricular ejection fraction; LVDd, left ventricular end diastolic diameter; LVDs, left ventricular end diastolic diameter; LA, left atrial diameter; IVS, Interventricular septum; RV, right ventricular diameter; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low density lipoprotein; BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TP, total protein; ALB, albumin; TBIL, total bile acids; TBA, total bile acids; UA, uric acid; Crea, creatinine; GFR, glomerular filtration rate; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte; MONO, mononuclear; EOS, eosinophils; BASO basophils; NEU-R, neutrophil rate; RBC, red blood cell; HB, hemoglobin; HCT, hematocrit; PLT, platelets; HbA1c, glycated hemoglobin. *P<0.05 for equality between C vs MV;§P<0.05 for equality between C vs SV.