TABLE 4.
Correlation degree between peak areas of 16 targeted compounds and hepatotoxicity.
| Compound | GRA (correlation) | OPLS (R value) | ||
|---|---|---|---|---|
| L02 | HepG2 | L02 | HepG2 | |
| X1 | 0.763 | 0.754 | 0.873 | 0.478 |
| X2 | 0.818 | 0.778 | –0.285 | 0.061 |
| X3 | 0.806 | 0.813 | 0.193 | –0.055 |
| X4 | 0.804 | 0.816 | –0.062 | –0.150 |
| X5 | 0.825 | 0.814 | –0.515 | –0.510 |
| X6 | 0.826 | 0.776 | –0.387 | –0.210 |
| X7 | 0.755 | 0.718 | –0.443 | –0.222 |
| X8 | 0.750 | 0.707 | 0.160 | 0.070 |
| X9 | 0.718 | 0.681 | –0.101 | –0.190 |
| X10 | 0.800 | 0.776 | –0.266 | –0.318 |
| X11 | 0.786 | 0.769 | –0.191 | –0.062 |
| X12 | 0.733 | 0.715 | 0.504 | 0.506 |
| X13 | 0.744 | 0.755 | 0.239 | 0.198 |
| X14 | 0.772 | 0.779 | –0.597 | –0.440 |
| X15 | 0.750 | 0.774 | 0.048 | –0.121 |
| X16 | 0.755 | 0.775 | –0.272 | –0.252 |