Table 2.

Establishment of the swimming fatigue model.

Species	Age	Sex	Duration	Weight-bearing	Reference
SD rats	8 weeks	male	Once a day for 3 h days 1–7 and twice a day for 6 h days 8–10	None	22
SD rats	9–10 weeks	male	30 min a day, days 1–2; days 3–5, increase 30 min a day until day 5 is up to 120 min	None	23
SD rats	6–8 weeks	male	20 min per day for 3 days, 3 weeks to exhaustion	5% of body weight	24
SD rats		male	Once every other day for 10 times	5% of body weight	25
ICR mice	6–8 weeks	male	Adaptation training for 1 week, 6 days/week, 30 and 45 min in days 1 and 2, 1 h in the following 4 days and the following training weeks	No weight for week 1; weeks 2–6, 2% of body weight per week until 10% is reached	26
Kunming mice	2 months	male	6 days a week, 60 min a day for 4 weeks	One group for 5% of body weight; one group, no load	27
ICR mice	4–6 weeks	male	Adaptation training for 1 week, 5 days/week, 30 and 45 min in days 1 and 2, 1 h in the following 3 days and the following training weeks	No weight for week 1; weeks 2–6, 10% of body weight	28
ICR mice	4 weeks	male	Adaptation training for 1 week, 30 and 45 min in days 1 and 2, 1 h in the following 3 days and the following training weeks	No weight for week 1, 1% in week 2, 2% in weeks 3–4, 3% in weeks 5–6. Finally, 5% of body weight was used to swim until exhaustion	29