Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Aug 26;14:910988. doi: 10.3389/fnagi.2022.910988

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Brandi, Torres-Garcia, Svanbergsson, Haikal, Liu, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Astrocytes heterogeneity in CX3CR1^+/GFP mice. (A) Percentage of marked area by GFAP positive astrocytes in vehicles C57BL6N and CX3CR1^+/GFP mice. Two-way ANOVA F_{Brain Regions} (15, 64) = 136.9, p < 0.0001. F_Genotype (1, 64) = 0.00128, p < 0.9715. F_Interaction (15, 64) = 3.575, p < 0.0002, and n = 3 mice per region. Significance: (*) respect relative regions in C57BL6 mice. (B) Changes in percentage of marked area by GFAP positive astrocytes in CX3CR1^+/GFP mice cells in vehicles (white columns) and LPS treated (black columns). Two-way ANOVA. F_{Brain Regions} (15, 64) = 39.36, p < 0.0001. F_Treatment (1, 64) = 5.526, p < 0.0218. F_Interaction (15, 64) = 0.9605, p < 0.5055, and n = 3 mice per region. Significance: (*) respect relative vehicles. (C) Confocal images of GFAP positive astrocytes in SNpr in C57BL6 and CX3CR1^+/GFP mice. (D) Representative images of GFAP positive astrocytes in hippocampus of CX3CR1^+/GFP mice treated with 5 mg/kg LPS and relative control.