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. 2022 Aug;13(4):1898–1906. doi: 10.21037/jgo-22-643

Table 2. Treatment-related adverse events in patients receiving an anti-PD-1 antibody plus lenvatinib.

TRAEs Any grade, n (%) Grade ≥3, n (%)
Appetite loss 20 (43.5) 4 (8.7)
Hypothyroidism 20 (43.5) 1 (2.2)
Hypertension 17 (36.9) 3 (6.5)
Fatigue 16 (34.8) 0
Diarrhea 12 (26.1) 2 (4.3)
Dysphonia 10 (21.7) 0
Weight loss 9 (19.6) 0
Hand-foot syndrome 8 (17.4) 0
Proteinuria 8 (17.4) 1 (2.2)
Hemorrhage 5 (10.9)
Immune pneumonia 2 (4.3)
Immune enteritis 1 (2.2)
Immune hepatitis 1 (2.2)
Rash 1 (2.2)
Shoulder pain 1 (2.2)
Thrombocytopenia 1 (2.2)

Table contains any TRAE reported in >5 (10%) patients and any TRAE ≥ grade 3. TRAEs, treatment-related adverse events.