Table 2. Treatment-related adverse events in patients receiving an anti-PD-1 antibody plus lenvatinib.
TRAEs | Any grade, n (%) | Grade ≥3, n (%) |
---|---|---|
Appetite loss | 20 (43.5) | 4 (8.7) |
Hypothyroidism | 20 (43.5) | 1 (2.2) |
Hypertension | 17 (36.9) | 3 (6.5) |
Fatigue | 16 (34.8) | 0 |
Diarrhea | 12 (26.1) | 2 (4.3) |
Dysphonia | 10 (21.7) | 0 |
Weight loss | 9 (19.6) | 0 |
Hand-foot syndrome | 8 (17.4) | 0 |
Proteinuria | 8 (17.4) | 1 (2.2) |
Hemorrhage | – | 5 (10.9) |
Immune pneumonia | – | 2 (4.3) |
Immune enteritis | – | 1 (2.2) |
Immune hepatitis | – | 1 (2.2) |
Rash | – | 1 (2.2) |
Shoulder pain | – | 1 (2.2) |
Thrombocytopenia | – | 1 (2.2) |
Table contains any TRAE reported in >5 (10%) patients and any TRAE ≥ grade 3. TRAEs, treatment-related adverse events.