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. 2022 Aug 26;12:938827. doi: 10.3389/fonc.2022.938827

Table 5.

The univariate and multivariate analyses of overall survival.

Univariate analyses Multivariate analyses
Median OS (95% CI) HR(95% CI) P value β S.E. Wald df HR(95% CI) P value
Gender(Female vs. Male) 2.046(0.909, 4.604) 0.084 0.275 0.439 0.394 1 1.317(0.557, 3.112) 0.530
 Male *26.54(22.61-30.47)
 Female 14.67(7.628-21.70)
Age 1.368(0.574, 3.260) 0.480
 <65 *26.34(20.43-32.24)
 ≥65 * 24.11(19.73-28.48)
Smoking history 1.312(0.582, 2.956) 0.512
 Non-smokers 21.00(13.91-28.01)
 Smokers *24.88(20.96-28.80)
Histology 1.307(0.567, 3.012) 0.530
 ADC *24.01(19.57-28.45)
 Non-ADC *25.94(20.76-31.13)
Histology 1.186(0.497, 2.826) 0.701
 SCC *25.49(19.76-31.21)
 Non-SCC *24.44(20.21-28.68)
Stage 1.736(0.596, 5.057) 0.312
 III *23.30(18.82-27.79)
 IV * 23.96(19.91-27.99)
Distant metastases 2.037(0.700, 5.928) 0.192 0.392 0.576 0.465 1 1.481(0.479, 4.577) 0.495
 Yes * 23.56(19.44-27.68)
 No * 23.77(19.62-27.91)
Tumor size 1.054(0.487, 2.285) 0.893
 <3 cm * 24.74(19.94-29.54)
 ≥3 cm * 25.07(19.94-30.19)
Camrelizumab treatment 1.184(0.546, 2.565) 0.669
 Monotherapy * 24.93(20.20-29.66)
 Combination * 24.15(18.74-29.57)
Treatment interval 1.096(0.502, 2.389) 0.818
 3 weeks * 25.32(20.20-30.43)
 2 weeks * 24.48(19.67-29.28)
Response to camrelizumab 15.10(6.830, 33.38) 0.0003 2.651 1.026 6.674 1 14.17(1.896, 105.8) 0.010
 CR+PR *not reached
 SD+PD *19.40(11.17-27.63)
Response to camrelizumab 9.850(1.035, 93.78) <0.0001
 CR+PR+SD * not reached
 PD *10.3(3.454-24.15)

*Mean overall survival. ADC, Adenocarcimona; CR, complete response; ECOG:Eastern Cooperation of Oncology Group;Non-ADC, Non-adenocarcinoma; Non-SCC: Non-squamous lung cancer; PD, Progression disease; PR, Partial response; SCC: Squamous cell lung cancer; SD, Stable disease.