FIGURE 2.

Hsa_circ_0129047 overexpression inhibited LUAD cell viability, migration and promoted cell apoptosis. (A) Hsa_circ_0129047 overexpression efficiency verified by RT‐qPCR after transfection with oe‐circ_0129047 vector. **p < 0.001 vs. Oe‐NC. (B) CCK‐8 assay was adapted to evaluate the cell viability in A549 and Calu‐3 cells transfected with oe‐NC and oe‐circ_0129047. *p < 0.05, **p < 0.001 vs. Oe‐NC. (C) Western blot experiment showed the expression of anti‐apoptotic marker Bcl‐2 and pro‐apoptotic marker Bax in A549 and Calu‐3 cells transfected with oe‐NC and oe‐circ_0129047. **p < 0.001 vs. Oe‐NC. (D) Cell migration ability was determined by Transwell assay in A549 and Calu‐3 cells transfected with oe‐NC and oe‐circ_0129047. **p < 0.001 vs. oe‐NC