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Binding reversibility of selected cathepsin V inhibitors. Cathepsin V activity measured after rapid 100-fold dilution of cathepsin V and inhibitor mixture. The mixture was diluted immediately or after 2 h of incubation. Recovery of enzyme activity after dilution with 2 h incubation points towards reversible binding of the inhibitor. Data are presented as mean ± SEM (n = 2). **P < 0.01, ****P < 0.0001 (Student's t-test).
