Table 2. Subgroup survival analysis for lung cancer patients with early- and advanced stages.
Stages | Sample sizes | OS | LCSS | |||||
---|---|---|---|---|---|---|---|---|
All death cases | 5-year OS rates† | P value‡ | Lung cancer death cases | 5-year LCSS rates† | P value‡ | |||
Early Stages¶ | 1,392 | 444 | <0.01 | 348 | <0.01 | |||
Small cell carcinoma | 71 | 39 | 47.9 (37.6–61.0) | 33 | 51.9 (41.2–65.5) | |||
Squamous cell carcinoma | 331 | 151 | 60.4 (55.4–65.9) | 116 | 66.6 (61.5–72.0) | |||
Adenocarcinoma | 887 | 217 | 79.0 (76.4–81.8) | 166 | 83.5 (81.1–86.0) | |||
Others†† | 103 | 37 | 69.9 (61.6–79.3) | 33 | 73.1 (64.9–82.3) | |||
Advanced Stages ‡‡ | 3,535 | 2725 | 0.09 | 2,306 | <0.05 | |||
Small cell carcinoma | 522 | 404 | 24.3 (20.9–28.3) | 350 | 28.7 (24.8–33.1) | |||
Squamous cell carcinoma | 818 | 604 | 28.0 (25.1–31.2) | 515 | 33.1 (29.8–36.6) | |||
Adenocarcinoma | 1,902 | 1496 | 25.6 (23.7–27.6) | 1,249 | 30.7 (28.6–33.0) | |||
Others | 293 | 221 | 25.6 (21.1–31.1) | 192 | 29.6 (24.6–35.7) | |||
Overall | 4,927§§ | 3169 | 37.0 (35.9–38.1) | – | 2,654 | 41.6 (40.5–42.8) | – |
†, survival rates were calculated by Kaplan-Meier method and were shown as rate (%) and its 95% CIs; ‡, P values were calculated by Log Rank test; ¶, including stage I and stage II; ††, including large cell carcinoma, carcinoid, sarcomatoid carcinoma, and adenosquamous carcinoma; ‡‡, including stage III and stage IV; §§, patient with specific information on both pathological stage and histological classification. OS, overall survival; LCSS, lung cancer specific survival; CIs, confidence intervals.