Table 6.
Effect of pitaya peel and pulp extracts on BAX, Bcl-2, caspase-9, and p53 protein expression levels in MCF-7 and Caco-2 cells 48 h after treatment.
| Protein Expression (Normalized to β-Actin) a | |||||
|---|---|---|---|---|---|
| BAX | Bcl-2 | BAX/Bcl-2 Ratio | Caspases-9 | p53 | |
| MCF-7 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Pulp extract | 1.49 | 0.66 | 2.22 | 1.25 | 1.44 |
| Peel extract | 2.64 | 0.39 | 6.14 | 2.22 | 2.63 |
| Caco-2 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Pulp extract | 2.20 | 0.70 | 3.14 | 1.26 | 2.25 |
| Peel extract | 3.70 | 0.62 | 5.96 | 2.30 | 2.01 |
a Values are presented as changes from the corresponding untreated cells, which was set to “1.”