Table 2.
Weighted odds ratios (95% confidence intervals) for sleep disorders across quartiles of pyridoxal 5′-phosphate (PLP) concentrations (NHANES 2005–2008).
| Cases/ Participants |
Crude | Model 1 a | Model 2 b | |
|---|---|---|---|---|
| Sleep disorders | ||||
| Q1 (<27.3) | 195/2428 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Q2 (27.3 to <44.0) | 153/2430 | 0.74 (0.54–1.03) | 0.77 (0.55–1.07) | 0.78 (0.53–1.16) |
| Q3 (44.0 to <76.3) | 141/2425 | 0.67 (0.49–0.90) ** | 0.67 (0.49–0.93) ** | 0.88 (0.61–1.28) |
| Q4 (≥76.3) | 150/2427 | 0.75 (0.55–1.03) | 0.74 (0.53–1.03) | 1.02 (0.66–1.58) |
| Trouble falling asleep | ||||
| Q1 (<27.3) | 447/2428 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Q2 (27.3 to <44.0) | 385/2430 | 0.77 (0.66–0.90) ** | 0.81 (0.69–0.96) * | 0.93 (0.76–1.14) |
| Q3 (44.0 to <76.3) | 334/2425 | 0.66 (0.54–0.79) ** | 0.72 (0.58–0.89) ** | 0.93 (0.72–1.19) |
| Q4 (≥76.3) | 342/2427 | 0.70 (0.58–0.84) ** | 0.76 (0.63–0.93) ** | 1.09 (0.87–1.36) |
| Wake up during the night | ||||
| Q1 (<27.3) | 541/2428 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Q2 (27.3 to <44.0) | 429/2430 | 0.72 (0.57–0.90) ** | 0.79 (0.63–0.98) ** | 0.92 (0.69–1.22) |
| Q3 (44.0 to <76.3) | 424/2425 | 0.68 (0.59–0.80) ** | 0.77 (0.66–0.90) ** | 0.98 (0.79–1.22) |
| Q4 (≥76.3) | 404/2427 | 0.63 (0.53–0.75) ** | 0.69 (0.58–0.82) ** | 0.89 (0.73–1.10) |
| Daytime sleepiness | ||||
| Q1 (<27.3) | 503/2428 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Q2 (27.3 to <44.0) | 382/2430 | 0.66 (0.55–0.79) ** | 0.67 (0.55–0.80) ** | 0.76 (0.59–0.99) * |
| Q3 (44.0 to <76.3) | 368/2425 | 0.62 (0.51–0.75) ** | 0.64 (0.53–0.77) ** | 0.78 (0.62–0.98) * |
| Q4 (≥76.3) | 373/2427 | 0.59 (0.51–0.69) ** | 0.63 (0.54–0.72) ** | 0.80 (0.64–1.00) |
Calculated using binary logistic regression models. a Model 1 adjusted for age and sex. b Model 2 adjusted for age, sex, race/ethnicity, education level, household poverty ratio, marital status, body mass index, physical activity, smoking status, caffeine intake, energy, alcohol consumption, hypertension, diabetes, depressive symptoms, and sampling season. * p < 0.05; ** p < 0.01.