Figure 8.

Effect of aqueous extract on the liver tissue. The liver of control mice group revealed intact hepatic portal vein and no hypertrophy in cells. Diabetic mice liver revealed hepatocyte hypertrophy and vein distortion (arrows). Metformin-treated mice revealed improvement in morphology of liver tissue (*). Furthermore, 500 mg/kg TS-AQ dose-treated mice showed restoration of normal structure of liver and size of hepatocyte was restored (*), and 800 mg/kg TS-AQ-treated mice revealed improvement in restoration of normal morphology of liver but there was some cellular infiltration (arrow). hh = hepatocyte hypertrophy. ci = cellular infiltration.