Table 5.
Differential expression of 33 transcripts based on fold change annotated to genes that are involved in inflammation mediated by chemokine and cytokine signaling pathway (High magnesium condition).
| Prob Set Name | Entrez Gene | Gene Symbol | Gene Title | Gene Ontology Biological Process | p-Value | Log2 Fold-Change |
|---|---|---|---|---|---|---|
| 207445_s_at | 10,803 | CCR9 | Chemokine (C-C motif) receptor 9 | Chemotaxis/inferred from electronic annotation/chemotaxis | 0.042 | 1.3 |
| 211230_s_at | 5293 | PIK3CD | Phosphoinositide-3-kinase, catalytic, delta polypeptide | B cell homeostasis/inferred from electronic annotation/ | 0.004 | 1.3 |
| 216834_at | 5996 | RGS1 | Regulator of G-protein signaling 1 | Immune response/traceable author statement/signal transduce | 0.047 | 1.2 |
| 230202_at | 5970 | RELA | Transcription factor p65 | Liver development/inferred from electronic annotation | 0.047 | 1.2 |
| 221244_s_at | 5170 | PDPK1 | 3-phosphoinositide dependent protein kinase-1 | Protein phosphorylation/inferred from electronic annotation/ | 0.022 | 1.2 |
| 224909_s_at | 57,580 | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | Superoxide metabolic process/traceable author statement | 0.019 | 1.1 |
| 210162_s_at | 4772 | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | G1/S transition of mitotic cell cycle/inferred from electronic annotation | 0.036 | 1.1 |
| 222912_at | 408 | ARRB1 | Arrestin, beta 1 | G-protein coupled receptor internalization/inferred from mutant phenotype | 0.015 | 1.1 |
| 203175_at | 391 | RHOG | Rho-related GTP-binding protein, member G (rho G) | Small GTPase mediated signal transduction/inferred from electronic annota | 0.035 | 1.1 |
| 212777_at | 6654 | SOS1 | Son of sevenless homolog 1 | Apoptosis/not recorded signal transduction | 0.017 | 1.1 |
| 211543_s_at | 2870 | GRK6 | G protein-coupled receptor kinase 6 | Protein phosphorylation/inferred from electronic annotation | 0.006 | 1.1 |
| 205884_at | 3676 | ITGA4 | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | Blood vessel remodeling inferred from electronic annotation | 0.029 | 1.1 |
| 205127_at | 5742 | PTGS1 | Prostaglandin-endoperoxide synthase 1 | Prostaglandin biosynthetic process/inferred from sequence or structural s | 0.017 | 1.1 |
| 33814_at | 10,298 | PAK4 | P21 protein (Cdc42/Rac)-activated kinase 4 | Protein phosphorylation/inferred from electronic annotation | 0.019 | 1.1 |
| 228388_at | 4793 | NFKBIB | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | Transcription/traceable author statement/signal transducti | 0.01 | 1.1 |
| 200885_at | 389 | RHOC | Rho-related GTP binding protein, member C | Small GTPase mediated signal transduction/inferred from electronic annota | 0.018 | 1.1 |
| 208075_s_at | 6354 | CCL7 | Chemokine (C-C motif) ligand 7 | Cellular calcium ion homeostasis/traceable author statement | 0.042 | 1.1 |
| 201188_s_at | 3710 | ITPR3 | Inositol 1,4,5-triphosphate receptor, type 3 | Transport/inferred from electronic annotation/ion transport | 0.038 | 1.1 |
| 225363_at | 5728 | PTEN | Phosphatase and tensin homolog | Regulation of cyclin-dependent protein kinase activity/traceable authors | 0.03 | 1.1 |
| 205125_at | 5333 | PLCD1 | Phospholipase C, delta 1 | Lipid metabolic process/inferred from electronic annotation/ | 0.03 | 1.1 |
| 201895_at | 369 | ARAF | Serine/threonine protein kinase A raf | Protein modification process/traceable author statement | p < 0.001 | 1.1 |
| 212647_at | 6237 | RRAS | Related RAS viral (r-ras) oncogene homolog | Signal transduction/inferred from electronic annotation | 0.041 | 1.1 |
| 224994_at | 817 | CAMK2D | Calcium/calmodulin-dependent protein kinase II delta | G1/S transition of mitotic cell cycle//inferred from electronic annotation | 0.038 | 1.1 |
| 206336_at | 6372 | CXCL6 | Chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | Chemotaxis/inferred from electronic annotation/chemotaxis | p < 0.001 | −1.8 |
| 211506_s_at | 3576 | IL8 | Interleukin 8 | Angiogenesis/traceable author statement/cellular component | 0.011 | −1.5 |
| 204470_at | 2919 | CXCL1 | Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | Chemotaxis/traceable author statement inflammatory response | 0.027 | −1.2 |
| 225139_at | 4775 | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | Transcription/inferred from electronic annotation | 0.033 | −1.0 |
| 204010_s_at | 3845 | KRAS | GTPase KRas | Apoptosis/inferred from electronic annotation/signal trans | 0.029 | −1.1 |
| 38290_at | 10,636 | RGS14 | Regulator of G-protein signaling 14 | Mitosis/inferred from electronic annotation/signal transduce | 0.001 | −1.1 |
| 204103_at | 6351 | CCL4 | Chemokine (C-C motif) ligand 4 | Cellular component movement/traceable author statement | 0.008 | −1.1 |
| 207952_at | 3567 | IL5 | Interleukin 5 (colony-stimulating factor, eosinophil) | Inflammatory response/inferred from electronic annotation | 0.024 | −1.1 |
| 213044_at | 6093 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | Cytokinesis/inferred from electronic annotation/protein ph | 0.002 | −1.1 |
| 209774_x_at | 2920 | CXCL2 | Chemokine (C-X-C motif) ligand 2 | Chemotaxis/inferred from electronic annotation/chemotaxis | 0.045 | −1.1 |