Table 7.
Differential expression of 28 transcripts based on fold change annotated to genes that are involved in inflammation mediated by chemokine and cytokine signalling pathway (Low magnesium condition).
| Prob Set Name | Entrez Gene | Gene Symbol | Gene Title | Gene Ontology Biological Process | p-Value | Log2 Fold-Change |
|---|---|---|---|---|---|---|
| 211230_s_at | 5293 | PIK3CD | Phosphoinositide-3-kinase, catalytic, delta polypeptide | B cell homeostasis/inferred from electronic annotation | 0.006 | 1.3 |
| 205127_at | 5742 | PTGS1 | Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | Prostaglandin biosynthetic process/inferred from sequence or structural | 0.008 | 1.2 |
| 221244_s_at | 5170 | PDPK1 | 3-phosphoinositide dependent protein kinase-1 | Protein phosphorylation/inferred from electronic annotation | 0.01 | 1.2 |
| 201188_s_at | 3710 | ITPR3 | Inositol 1,4,5-triphosphate receptor, type 3 | Transport/inferred from electronic annotation ion transpor | 0.03 | 1.2 |
| 233254_x_at | 5728 | PTEN | Phosphatase and tensin homolog | Regulation of cyclin-dependent protein kinase activity/traceable authors | 0.006 | 1.2 |
| 232043_at | 2788 | GNG7 | Guanine nucleotide binding protein (G protein), gamma 7 | Behavioral fear response/inferred from electronic annotation | 0.03 | 1.1 |
| 1568926_x_at | 91,807 | MYLK3 | Myosin light chain kinase 3 | Protein phosphorylation/inferred from electronic annotation | 0.018 | 1.1 |
| 216190_x_at | 3688 | ITGB1 | Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, M | G1/S transition of mitotic cell cycle/inferred from electronic annotation | 0.014 | 1.1 |
| 224994_at | 817 | CAMK2D | Calcium/calmodulin-dependent protein kinase II delta | G1/S transition of mitotic cell cycle//inferred from electronic annotation | 0.01 | 1.1 |
| 205962_at | 5062 | PAK2 | P21 protein (Cdc42/Rac)-activated kinase 2 | Protein phosphorylation/inferred from direct assay/protein | 0.017 | 1.1 |
| 243829_at | 673 | BRAF | V-raf murine sarcoma viral oncogene homolog B1 | MAPKKK cascade/inferred from electronic annotation/protein | 0.003 | 1.1 |
| 210162_s_at | 4772 | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | G1/S transition of mitotic cell cycle/inferred from electronic annotation | 0.04 | 1.1 |
| 209201_x_at | 7852 | CXCR4 | Chemokine (C-X-C motif) receptor 4 | Activation of MAPK activity traceable author statement | 0.01 | −1.3 |
| 1560524_at | 400,581 | GRAP | GRB2-related adaptor protein | Ras protein signal transduction/traceable author statement | 0.03 | −1.2 |
| 224965_at | 54,331 | GNG2 | Guanine nucleotide binding protein (G protein), gamma 2 | Signal transduction/inferred from electronic annotation | 0.01 | −1.2 |
| 208641_s_at | 5879 | RAC1 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | Endocytosis/inferred from electronic annotation/apoptosis | 0.01 | −1.1 |
| 204174_at | 241 | ALOX5AP | Arachidonate 5-lipoxygenase-activating protein | Leukotriene production involved in inflammatory response/inferred from el | 0.04 | −1.1 |
| 222912_at | 408 | ARRB1 | Arrestin, beta 1 | G-protein coupled receptor internalization/inferred from mutant phenotype | 0.04 | −1.1 |
| 201179_s_at | 2773 | GNAI3 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | Transport/non-traceable author statement/vesicle fusion/ | 0.007 | −1.1 |
| 212590_at | 22,800 | RRAS2 | Related RAS viral (r-ras) oncogene homolog 2 | Signal transduction/inferred from electronic annotation | 0.013432 | −1.1 |
| 204103_at | 6351 | CCL4 | Chemokine (C-C motif) ligand 4 | Cellular component movement/traceable author statement | 0.01 | −1.1 |
| 225141_at | 4775 | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | Transcription/inferred from electronic annotation | 0.036 | −1.1 |
| 202647_s_at | 4893 | NRAS | Neuroblastoma RAS viral (v-ras) oncogene homolog | Apoptosis/inferred from electronic annotation/signal trans | 0.005 | −1.1 |
| 211434_s_at | 9034 | CCRL2 | Chemokine (C-C motif) receptor-like 2 | Chemotaxis/traceable author statement/signal transduction | 0.03 | −1.1 |
| 39402_at | 3553 | IL1B | Interleukin 1, beta | Activation of MAPK activity/inferred from direct assay | 0.02 | −1.1 |
| 203154_s_at | 10,298 | PAK4 | P21 protein (Cdc42/Rac)-activated kinase 4 | Protein phosphorylation/inferred from electronic annotation | 0.03 | −1.05 |
| 38290_at | 10,636 | RGS14 | Regulator of G-protein signaling 14 | Mitosis/inferred from electronic annotation/signal transdu | 0.004 | −1.0 |
| 207157_s_at | 2787 | GNG5 | Guanine nucleotide binding protein (G protein), gamma 5 | Signal transduction/non-traceable author statement/signal | 0.03 | −1.0 |