Table 2.

Differently expressed proteins across brain regions in early PD (Braak stage 3/4) compared to controls

	Upregulated	Downregulated	Total
Substantia nigra	159	301	460
Caudate	59	63	122
Putamen	69	96	165
Parahippocampus	72	100	172
Temporal cortex	45	64	109
Cingulate cortex	60	63	123
Frontal cortex	118	93	211
Parietal cortex	55	70	125
Cerebellum	58	70	128

The number of proteins that had an up- or down- regulation with > 1.5 fold expression according to each brain region tested