Table 2.
Regions with static amplitudes of low-frequency fluctuations in patients with CTN
| Brain region | Side | Peak MNI coordinates | Cluster size (voxels) |
Peak intensity | F value | P value | Post hoc P value | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| X | Y | Z | Baseline vs 5 s | Baseline vs 30 min | 5 s vs 30 min | ||||||
| Superior temporal gyrus | L | –60 | –3 | –15 | 51 | 12.803 | 40.425 | 0.000 | 0.000 | 0.000 | 0.915 |
| Middle temporal gyrus | R | 42 | –33 | –6 | 82 | 22.348 | 48.346 | 0.000 | 0.000 | 0.000 | 0.038 |
| Middle occipital gyrus | L | –42 | –72 | 9 | 121 | 23.398 | 26.863 | 0.000 | 0.000 | 0.000 | 0.114 |
| Thalamus | R | 27 | –12 | 9 | 59 | 16.632 | 20.324 | 0.000 | 0.000 | 0.049 | 0.003 |
| Middle occipital gyrus | R | 36 | –87 | –3 | 146 | 15.357 | 17.979 | 0.000 | 0.179 | 0.000 | 0.000 |
| cuneus | R | –6 | –84 | 27 | 1334 | 25.222 | 17.062 | 0.000 | 0.550 | 0.000 | 0.000 |
| Posterior cingulate cortex | L | –9 | –45 | 27 | 148 | 17.867 | 20.956 | 0.000 | 0.000 | 0.000 | 0.913 |
| Superior frontal gyrus | L | –6 | 24 | 60 | 137 | 15.193 | 15.867 | 0.000 | 0.001 | 0.000 | 0.000 |
| Superior frontal gyrus | R | 18 | 3 | 69 | 72 | 17.820 | 25.028 | 0.000 | 0.000 | 0.000 | 0.004 |
Baseline, the rs-fMRI was performed before stimulating the trigger zone; 5 s, the rs-fMRI was performed within 5 s after stimulating the trigger zone; 30 min, the rs-fMRI was performed in the 30th minute after stimulating the trigger zone
CTN Classical trigeminal neuralgia, L Left, R Right, MNI Montreal Neurological Institute