TABLE 5.

Significant multivariable relations between patient/caregiver reports of being on hydroxyurea and provider prescription of hydroxyurea.

Model	Variable	Odds ratio (95%confidence interval)
Patient/Caregiver report of being on hydroxyurea
	Age
	12 years and younger	Reference
	13–17 years	1.9 (0.66–5.2)
	18–25 years	0.48 (0.15–1.53)
	26 years and older	0.13 (0.04–0.38)**
	Total Barriers
	None	Reference
	1 barrier	0.08 (0.03–0.20)***
	2 or more barriers	0.19 (0.07–0.57)*
	Indication—Recurrent Pain	811.5 (87.7–7504.3)***
	Not Interested in hydroxyurea	0.06 (0.01–0.31)**
Provider prescription of hydroxyurea
	Age
	12 years and younger	Reference
	13–17 years	1.1 (0.56–2.1)
	18–25 years	0.65 (0.33–1.30)
	26 years and older	0.45 (0.25–0.78)*
	Total Barriers
	None	Reference
	1 barrier	0.15 (0.09–0.26)***
	2 or more barriers	0.27 (0.14–0.52)**
	Diagnosis
	HgbSS and HgbSβ0 thalassemia	Reference
	HgbSC	0.21 (0.10–0.41)***
	Other diagnoses	0.35 (0.13–0.90)

*p < 0.01, **p < 0.001, ***p < 0.0001.