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Inhibition of ferroptosis attenuates IRE1/JNK pathway in mice after I/R and HK-2 cells after H/R. Western blotting detection (A) and protein synthesis (B) of p-IRE1α, p-JNK, and CHOP in mice at 48 h after I/R. Due to the death of mice, N = 5 for each group. Western blotting detection (C) and protein synthesis (D) of p-IRE1α, p-JNK, and CHOP in HK-2 cells at 12 h after H/R. Statistical significance is denoted as *: p < 0.05, **: p < 0.01 in two groups.
