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. 2022 Aug 26;10:946992. doi: 10.3389/fbioe.2022.946992

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Copyright © 2022 Deckers, Hall, Papantoniou, Aerts and Bloemen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Normalized contact length and averaged intersphere angle. (A,B) Average response ±SEM of the normalized contact length for the different maturation stages, respectively, for the Y and V pools. (C,D) Box plots of the integration rate, i.e., the slope extracted from the linear model fit on the normalized contact length (data up to 5 h were considered), for the different maturation stages, respectively, for the Y and V pools. Data were compared with one-way ANOVA and the Tukey–Kramer post hoc test. Significance was visualized with *: p < 0.05; **: p < 0.01; ***: p < 0.001. (E,F) Average response ±SEM of the averaged intersphere angle for the different levels of maturation, respectively, for the Y and V pools. 20–35 doublet samples were analyzed per condition.