TABLE 3.

Relative and absolute errors obtained for the different features with respect to manual feature annotation. The quantification was separated in function of the maturation time and the feature extraction procedure (before and after a roundness of 0.8), with the number of samples (N) indicated for each set. The results are represented as mean ± SD.

	D1	D7	D14	D21	Total
Roundness <0.8	n = 62	n = 126	n = 196	n = 98	n = 482
Doublet area (relative)	2.25 ± 1.97	1.54 ± 1.92	1.68 ± 1.22	1.47 ± 1.54	1.67 ± 1.61
Doublet length (relative)	1.26 ± 1.16	1.19 ± 1.17	1.18 ± 1.24	1.62 ± 1.87	1.28 ± 1.37
Doublet roundness (absolute)	0.0083 ± 0.0072	0.0107 ± 0.0102	0.0100 ± 0.0104	0.0102 ± 0.0100	0.0100 ± 0.0099
Contact length (relative)	2.30 ± 1.89	2.85 ± 2.30	2.75 ± 2.77	4.66 ± 5.01	3.11 ± 3.27
Averaged spheroid width (relative)	1.91 ± 1.93	1.57 ± 1.55	2.12 ± 1.81	1.80 ± 1.57	1.89 ± 1.72
Averaged intersphere angle (absolute)	12.27 ± 11.93	10.70 ± 8.47	10.19 ± 9.51	13.44 ± 10.94	11.25 ± 9.96
Roundness >0.8	n = 138	n = 83	n = 75	n = 74	n = 370
Doublet area (relative)	1.89 ± 1.48	1.60 ± 1.16	2.26 ± 1.97	1.23 ± 0.98	1.77 ± 1.48
Doublet length (relative)	1.56 ± 1.45	1.95 ± 1.73	1.43 ± 1.59	1.16 ± 1.02	1.54 ± 1.49
Doublet width (relative)	1.54 ± 1.38	1.54 ± 1.33	2.01 ± 1.92	2.27 ± 2.04	1.78 ± 1.66
Doublet roundness (absolute)	0.0111 ± 0.0112	0.0107 ± 0.0107	0.0135 ± 0.0140	0.0124 ± 0.0105	0.0118 ± 0.0116