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. 2022 Sep 7;8(2):e002359. doi: 10.1136/rmdopen-2022-002359

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Efficacy of biological disease modifying antirheumatic drugs targeting the IL-6 receptor or ligand and their relative efficacy and/or regulatory approvals across immune-mediated inflammatory diseases (based on available data at end of December 2020). aNCT02991469 (recruiting); bNCT02776735 (recruiting); cNCT03600805 (study terminated, results are awaited); d trial terminated early due to sponsor decision. For colorblind readers, figure 2 is provided in the online supplemental appendix (section 7: S7.1). EU, European Union; JPN, Japan; RU: Russian Federation; US: United Stated of America.