Table 3. Results of the incidence trend analysis of inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC) and unclassified IBD (IBD-U) by sex and age groups (AG) using joinpoint regression and annual percent change (APC) over the period 2000–2014.
| disease | sex/ AG | segment start—end | APC | [95% CI] | p-value | |
|---|---|---|---|---|---|---|
| CD | all | c. p. | + 3.3 | [0.0–6.7] | 0.049* | |
| CD | male | c. p. | + 4.5 | [0.6–8.5] | 0.027* | |
| CD | female | c. p. | + 1.6 | [− 3.2–6.7] | 0.486 | |
| CD | AG 0–9 | c. p. | + 0.8 | [− 5.0–6.9] | 0.779 | |
| CD | AG 10–14 | c. p. | + 4.1 | [1.2–7.2] | 0.009* | |
| UC | all | c. p. | + 1.4 | [− 2.0–4.9] | 0.406 | |
| UC | male | c. p. | + 1.8 | [− 3.1–6.9] | 0.456 | |
| UC | female | c. p. | − 0.1 | [− 5.2–5.3] | 0.970 | |
| UC | AG 0–9 | c. p. | + 1.5 | [− 9.7–14.0] | 0.794 | |
| UC | AG 10–14 | c. p. | + 1.0 | [− 2.4–4.5] | 0.537 | |
| IBD-U | no estimation is possible due to zero values | |||||
| IBD | all | c. p. | + 3.0 | [0.2–5.8] | 0.037* | |
| IBD | male | c. p. | + 4.0 | [0.8–7.3] | 0.018* | |
| IBD | female | 2000–2002 | + 47.8 | [− 25.9–194.9] | 0.237 | |
| IBD | female | 2002–2014 | − 0.9 | [− 4.6–2.9] | 0.593 | |
| IBD | AG 0–9 | c. p. | + 2.1 | [− 4.4–9.0] | 0.512 | |
| IBD | AG 10–14 | 2000–2002 | + 32.1 | [− 8.7–91.1] | 0.124 | |
| IBD | AG 10–14 | 2002–2014 | + 1.1 | [− 1.1–3.3] | 0.283 | |
c. p. = complete period, CI = confidence interval
* = significant