Table 2. Analyses of risk factors for PACG in patients with and without RP.
| Predictive variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | p-value | Model 1 | Model 2 | |||
| Adjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | |||
| RP (Yes vs. No) | 2.09 (1.64–2.65) | <0.0001 | 2.04 (1.60–2.59) | <0.0001 | 2.18 (1.76–2.72) | <0.0001 |
| Age | ||||||
| <40 | Reference | Reference | ||||
| 40–60 | 4.73 (2.87–7.80) | <0.0001 | 4.55 (2.74–7.57) | <0.0001 | ||
| ≥60 | 12.75(7.80–20.71) | <0.0001 | 12.51 (7.47–20.97) | <0.0001 | ||
| Sex (Male vs. Female) | 0.65 (0.51–0.82) | <0.001 | 0.71 (0.56–0.90) | <0.01 | ||
| Hypertension | 2.25 (1.79–2.83) | <0.0001 | 1.08 (0.87–1.35) | 0.473 | 1.31 (0.89–1.46) | 0.30 |
| Diabetes | 2.20 (1.73–2.79) | <0.0001 | 1.35 (1.03–1.77) | <0.05 | 1.64 (1.32–2.04) | <0.0001 |
| Hyperlipidaemia | 1.91 (1.52–2.40) | <0.0001 | 1.11 (0.86–1.44) | 0.428 | 1.22 (0.93–1.60) | 0.15 |
| Chronic kidney disease | 1.03 (0.66–1.65) | 0.855 | 1.01 (0.80–1.37) | 0.738 | 1.15 (0.86–1.51) | 0.36 |
| Cataract | 7.25 (5.73–9.17) | <0.0001 | 3.94 (2.99–5.20) | <0.0001 | ||
| Lens subluxation | 2.60 (1.23–5.50) | 0.03 | 1.06 (0.55–2.21) | 0.828 | 1.69 (0.85–3.49) | 0.13 |
Variables included in model 1: RP, age, sex, hypertension, diabetes, hyperlipidaemia, chronic kidney disease, cataract, lens subluxation.
Variables included in model 2: RP, hypertension, diabetes, hyperlipidaemia, chronic kidney disease, lens subluxation.
RP, retinitis pigmentosa; PACG, primary angle-closure glaucoma; HR, hazard ratio; CI, confidence interval.