Table 1.

Significant differentially expressed genes. LNCaP cells were transduced to express AR‐WT, AR‐Q641X, AR‐V7, or the empty eGFP plasmid (control) and were exposed to DHT or vehicle (EtOH) as indicated. Gene expression levels in the presence of DHT‐activated AR‐WT, AR‐Q641X_EtOH, or AR‐V7_EtOH (Datasets A) were compared with the reference dataset B corresponding to Control_EtOH. The number of differentially expressed genes with adjusted p‐value < 0.05 and |log₂FC| > 1 is indicated. The number of under‐ and overexpressed genes, A < B and A > B, respectively, is also indicated.

Condition	RNA‐seq datasets comparison (A vs B)	Number of differentially expressed genes	Number of underexpressed genes (A < B)	Number of overexpressed genes (A > B)
Control (eGFP)	Control_DHT vs Control_EtOH	649	183	466
AR‐WT	AR‐WT_DHT vs Control_EtOH	860	395	465
AR‐Q641X	AR‐Q641X_EtOH vs Control_EtOH	1558	78	1480
AR‐V7	AR‐V7_EtOH vs Control_EtOH	1091	71	1020