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MiR-563 loaded engineered Exo inhibits the migration and invasion of A549 cells. (a) The influence of miR-563 Exo on the migration ability of A549 cells assessed via scratch test. Scale bar = 200 nm (b). Transwell assay evaluated the migration and invasion capacity of A549 treated with miR-563 Exo. Scale bar = 200 nm (c). The protein expression of MMP2 and MMP9 evaluated by western blot. The values were presented as mean ± SD (n = 3). ∗∗∗P < 0.001 versus the unloaded Exo group.
