Table 2.
Selected malnutrition vaccines in development
| Disease | Vaccine/antigens | Organization or company | Stage of development | Refs |
|---|---|---|---|---|
| Hookworm infection | Hookworm vaccine | Texas Children’s CVD & HookVac Consortium | Phase 1–2 trials | [6] |
| Schistosomiasis | Sm-TSP-2 Sm-14 Sm-p80 |
Texas Children’s CVD FIOCRUZ PAI Life Sciences |
Phase 1 or 2 trials | [7] |
| Malaria | Mosquirix R21/Matrix-M PfSPZ Sporozoite |
GSK-PATH SII–Oxford University–Sanaria |
EMA Licensure and WHO approval infants 6–17 months Phase 2–3 Phase 2–3 |
[8,9] |
| Shigella | InvaplexAR-DETOX Shigella flexneri 2a conjugate AltSonflex1-2-3 |
WRAIR-PATH Institut Pasteur–WRAIR-PATH GSK Vaccines Institute for Global Health–PATH |
Phase 1 or 2 trials | [10]iii |
| ETEC and ETEC/Shigella combinations | ETVAX CssBA ShigETEC CVD 1208S-122 |
Scandanavian Biopharma NMRC-WRAIR-PATH Eveliqure University of Maryland CVD–Emergent BioSolutions |
Phase 1 or 2 trials | [11,12] |
| Tuberculosis | VPM1002 M72-AS01 MIP GamTBVac |
SII-Max Planck–VPM IAVI–GSK–Gates MRI Cadilla Russian Ministry of Health |
Phase 3 trials | [13] |