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. 2022 Sep 9;12:15246. doi: 10.1038/s41598-022-19607-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PBM increased undifferentiated/early neuronal cell population in the DG of the hippocampus after SE. (A) Representative coronal section views of Z-stacks obtained by confocal microscopy show the localization of DCX positive cells in the SGZ of the hippocampal DG. Immunostaining was performed with NeuN (for mature neuron, red) and DCX (for immature neuron, green). Scale bar 100 µm. (B) Quantification of the DCX fluorescent intensity in SGZ are shown. Expression of DCX fluorescent intensity are increased in 180 J PBM treated groups compared to the SE group only at 14 day. The quantitative data are presented as the mean ± SEM. *P < 0.05 compared with to SE group. (C) Quantification of the DCX positive cells in SGZ are shown. DCX positive cells are increased in 180 J PBM treated groups compared to the SE group only at 14 day. The quantitative data are presented as the mean ± SEM. ***P < 0.001 compared with to SE group. This figure was generated with Microsoft Visio version 2016 (Microsoft, Redmond, WA, USA).