Table 3.

Effects of neurotrophins on microRNAs expression

Neurotrophin	miRNA		Types of Research	Types of cell or model	Ref
	Upregulation	Downregulation
NGF	miR-221/222	-	In vitro	PC12 cell line	112
	miR-34a	-	In vitro	PC12 cell line	54
	miR-34, miR-181a, miR-200, miR-326	miR-106b, miR-126, miR-139-3p, miR-143, miR-210, miR-532-3p	In vitro	PC12 cell line	59
	-	miR-541	In vitro	PC12 cell line	114
	miR-132	miR-221	In vivo	Sprague–Dawley rats	116
	-	miR-494	In vitro	Human corneal epithelial cell	117
	-	Let-7b, Let-7d, Let-7i, miR-98	In vitro	Muller cells isolated from retina	120
	-	miR-21	In vitro	PC12 cell line	121
	-	miR-181d	In vitro	Primary sensory neurons	119
BDNF	miR-212	-	In vitro	Cortical neuron culture	12
	miR-132	-	In vitro	Cortical neuron cell culture	126
	miR-125b	-	In vitro	SH-SY5Y cells	125
	-	miR-134	In vitro	Primary hippocampal cultures	130
	-	miR-155-5p	In vivo	Experimental autoimmune encephalomyelitis mice model	153