| Vancomycin plus piperacillin–tazobactam was associated with an increased risk of creatinine-defined acute kidney injury, but not changes in alternative kidney function biomarkers (cystatin C, blood urea nitrogen), or downstream clinical outcomes associated with true acute kidney injury (dialysis or mortality). These findings suggest that the association of vancomycin + piperacillin–tazobactam with creatinine-defined acute kidney injury may represent pseudotoxicity |
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