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. 2022 Aug 29;8(9):e10453. doi: 10.1016/j.heliyon.2022.e10453

Table 2.

Efflux pump inhibitory activities of compounds isolated from C. trifoliata.

Compound Concentration (μM) FL-1 FAR
Tariquidar 0.2 88.20 11.44
imperatorin (1) 2 11.30 1.47
20 9.82 1.27
phellopterin (2) 2 11.10 1.44
20 20.30 2.63
scoparone (3) 2 8.01 1.04
20 15.60 2.02
myrsellin (4) 2 10.90 1.41
20 37.50 4.86
auraptene (5) 2 13.60 1.76
20 30.80 4.00
triphasiol (6) 2 14.20 1.84
20 14.30 1.85
limonin (9) 2 2.92 0.38
20 10.00 1.30
deacetyl nomilin (10) 2 4.61 1.01
20 3.53 0.78

FL-1: mean fluorescence intensity of the cells; FAR: fluorescence activity ratio.