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. 2022 Sep 1;8(9):e10498. doi: 10.1016/j.heliyon.2022.e10498

Table 6.

Antiwrinkle activity (IC50 values) of 50% ethanolic C. aurantium flower extract, unfermented and fermented by L. brevis.

Collagenase activity (mg/L) Elastase activity (mg/L) MMP-1 activity (mg/L) MMP-2 activity (mg/L)
50% ethanolic extract 315.6 ± 27.4b 502.8 ± 32b 864.3 ± 36.8b 912.0 ± 52.3b
L. brevis–fermented extract 73.5 ± 11.3a 85.2 ± 7.2a 152.4 ± 14.8a 175.2 ± 16.2a

In each column, letters (a–b) indicate P < 0.01.