Table 1.
Peak coordinates and primary brain regions for the 53 components (ICs) obtained using scICA (Neuromark framework) on the fMRI time series data. The 53 components were divided into 7 subdomains (resting-state networks) as shown in different colors in the table. The time-series from every possible pair of these 53 components was used to compute the static functional connectivity (SFNC) features using Pearson correlation. The SFNC features were then divided into 28 subdomain interactions (SDIs) based on the subdomain(s) to which a given pair of components for the SFNC feature belongs (See Figure 4).
| Primary region for component (IC ID) | X | Y | Z | Subdomain | Primary region for component (IC ID) | X | Y | Z | Subdomain |
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Caudate (69) | 6.5 | 10.5 | 5.5 | Inferior parietal lobule ([IPL], 68) | 45.5 | −61.5 | 43.5 | ||
| Subthalamus/hypothalamus (53) | −2.5 | −13.5 | −1.5 | Insula (33) | −30.5 | 22.5 | −3.5 | ||
| Putamen (98) | −26.5 | 1.5 | −0.5 | Subcortical | Superior medial frontal gyrus ([SMFG], 43) | −0.5 | 50.5 | 29.5 | |
| Caudate (99) | 21.5 | 10.5 | −3.5 | Inferior frontal gyrus ([IFG], 70) | −48.5 | 34.5 | −0.5 | ||
| Thalamus (45) | −12.5 | −18.5 | 11.5 | Right inferior frontal gyrus ([R IFG], 61) | 53.5 | 22.5 | 13.5 | ||
| Superior temporal gyrus ([STG], 21) | 62.5 | −22.5 | 7.5 | Auditory | Middle frontal gyrus ([MiFG], 55) | −41.5 | 19.5 | 26.5 | |
| Middle temporal gyrus ([MTG], 56) | −42.5 | −6.5 | 10.5 | Inferior parietal lobule ([IPL], 63) | −53.5 | −49.5 | 43.5 | ||
| Postcentral gyrus ([PoCG], 3) | 56.5 | −4.5 | 28.5 | Left inferior parietal lobue ([R IPL], 79) | 44.5 | −34.5 | 46.5 | ||
| Left postcentral gyrus ([L PoCG], 9) | −38.5 | −22.5 | 56.5 | Supplementary motor area ([SMA], 84) | −6.5 | 13.5 | 64.5 | Cognitive Control | |
| Paracentral lobule ([ParaCL], 2) | 0.5 | −22.5 | 65.5 | Superior frontal gyrus ([SFG], 96) | −24.5 | 26.5 | 49.5 | ||
| Right postcentral gyrus ([R PoCG], 11) | 38.5 | −19.5 | 55.5 | Middle frontal gyrus ([MiFG], 88) | 30.5 | 41.5 | 28.5 | ||
| Superior parietal lobule ([SPL], 27) | −18.5 | −43.5 | 65.5 | Sensorimotor | Hippocampus ([HiPP], 48) | 23.5 | −9.5 | −16.5 | |
| Paracentral lobule ([ParaCL], 54) | −18.5 | −9.5 | 56.5 | Left inferior parietal lobue ([L IPL], 81) | 45.5 | −61.5 | 43.5 | ||
| Precentral gyrus ([PreCG], 66) | −42.5 | −7.5 | 46.5 | Middle cingulate cortex ([MCC], 37) | −15.5 | 20.5 | 37.5 | ||
| Superior parietal lobule ([SPL], 80) | 20.5 | −63.5 | 58.5 | Inferior frontal gyrus ([IFG], 67) | 39.5 | 44.5 | −0.5 | ||
| Postcentral gyrus ([PoCG], 72) | −47.5 | −27.5 | 43.5 | Middle frontal gyrus ([MiFG], 38) | −26.5 | 47.5 | 5.5 | ||
| Calcarine gyrus ([CalcarineG], 16) | −12.5 | −66.5 | 8.5 | Hippocampus ([HiPP], 83) | −24.5 | −36.5 | 1.5 | ||
| Middle occipital gyrus ([MOG], 5) | −23.5 | −93.5 | −0.5 | Precuneus(32) | −8.5 | −66.5 | 35.5 | ||
| Middle temporal gyrus ([MTG], 62) | 48.5 | −60.5 | 10.5 | Precuneus(40) | −12.5 | −54.5 | 14.5 | ||
| Cuneus(15) | 15.5 | −91.5 | 22.5 | Anterior cingulate cortex ([ACC], 23) | −2.5 | 35.5 | 2.5 | ||
| Rightmiddle occipital gyrus ([R MOG], 12) | 38.5 | −73.5 | 6.5 | Visual | Posterior cingulate cortex ([PCC], 71) | −5.5 | −28.5 | 26.5 | Default mode |
| Fusiform gyrus (93) | 29.5 | −42.5 | −12.5 | Anterior cingulate cortex ([ACC], 17) | −9.5 | 46.5 | −10.5 | ||
| Inferior occipital gyrus ([IOG], 20) | −36.5 | −76.5 | −4.5 | Precuneus (51) | −0.5 | −48.5 | 49.5 | ||
| Lingual gyrus ([LingualG], 8) | −8.5 | −81.5 | −4.5 | Posterior cingulate cortex ([PCC], 94) | −2.5 | 54.5 | 31.5 | ||
| Middle temporal gyrus ([MTG], 77) | −44.5 | −57.5 | −7.5 | Cerebellum ([CB], 13) | −30.5 | −54.5 | −42.5 | Cerebellum | |
| Cerebellum ([CB], 18) | −32.5 | −79.5 | −37.5 | ||||||
| Cerebellum ([CB], 4) | 20.5 | −48.5 | −40.5 | ||||||
| Cerebellum ([CB], 7) | 30.5 | −63.5 | −40.5 | ||||||