Table 8.
EQ-5D-5L utilities and MRB-QoL total burden score, by time point and group
| Intervention | Control | Difference (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Missing n (%) |
Floor effects n (%) |
Ceiling effects n (%) |
Mean (95% CI) |
Missing n (%) |
Floor effects n (%) |
Ceiling effects n (%) |
Mean (95% CI) | ||
| EQ-5D-5L | |||||||||
| Baseline | 2 (5.4) | - | 6 (20.0) | 0.74 (0.64, 0.83) | 1 (3.3) | - | 8 (21.6) | 0.73 (0.65, 0.82) | 0.01 (−0.11, 0.13) |
| nI = 37 | |||||||||
| nC = 30 | |||||||||
| 6 months | 0 (0) | - | 4 (15.4) | 0.75 (0.67, 0.83) | 0 (0) | - | 5 (23.8) | 0.74 (0.63, 0.84) | 0.02 (−0.11, 0.14) |
| nI = 26 | |||||||||
| nC = 21 | |||||||||
| 9 months | 1 (4.0) | - | - | 0.72 (0.61, 0.83) | 0 (0) | - | - | 0.77 (0.68, 0.86) | −0.05 (−0.19, 0.08) |
| nI = 25 | |||||||||
| nC = 22 | |||||||||
| MRB-QoL | |||||||||
| Baseline | 5 (13.5) | - | 2 (5.4) | 23.79 (18.23, 29.35) | 4 (13.3) | - | 3 (10.0) | 26.52 (18.75, 33.30) | −2.73 (−11.85, 6.39) |
| nI = 37 | |||||||||
| nC = 30 | |||||||||
| 6 months | 3 (11.5) | - | 2 (7.7) | 21.49 (15.12, 27.87) | 7 (33.3) | - | 2 (9.5) | 24.71 (12.82, 36.61) | −3.22 (−15.02, 8.59) |
| nI = 26 | |||||||||
| nC = 21 | |||||||||
| 9 months | 2 (8.0) | - | 2 (8.0) | 22.44 (15.24, 29.64) | 4 (18.2) | - | 4 (18.2) | 25.27 (15.40, 35.13) | −2.83 (−14.35, 8.70) |
| nI = 25 | |||||||||
| nC = 22 | |||||||||
nI, nC number of patients in intervention (I) and control (C) after withdrawals, CI confidence intervals