Table 3.
HRQoL, WPAI, HRU and comorbidities among mild and severe CC patients in South Korea and Taiwan.
| South Korea (N = 101) |
|||||
|---|---|---|---|---|---|
| Mild CC (VAS≤4) (N = 58) |
Severe CC (VAS>4) (N = 43) |
P-value | |||
| Mean | 95% LCL–95% UCL | Mean | 95% LCL–95% UCL | ||
| HRQoL | |||||
| Physical Component Summary Score | 49.48 | 47.77–51.19 | 45.80 | 43.82–47.78 | 0.006 |
| Mental Component Summary Score | 44.95 | 42.70–47.20 | 43.15 | 40.55–45.75 | 0.303 |
| SF-6D Health Utilities Score | 0.69 | 0.67–0.72 | 0.68 | 0.65–0.71 | 0.500 |
| EQ-5D-5L Health Utilities Score | 0.77 | 0.71–0.82 | 0.67 | 0.61–0.74 | 0.030 |
| WPAI | |||||
| Absenteeism (N = 42/32) | 3.6% | 2.1%–6.2% | 8.5% | 4.7%–15.5% | 0.047 |
| Presenteeism (N = 42/33) | 29.8% | 23.0%–38.8% | 33.7% | 25.1%–45.4% | 0.550 |
| Total work productivity impairment (N = 42/32) | 31.8% | 24.6%–41.1% | 37.9% | 28.2%–50.9% | 0.392 |
| Total activity Impairment | 30.0% | 24.3%–37.1% | 37.3% | 29.4%–47.4% | 0.184 |
| HRU | |||||
| No. of HCP visits in past 6 months | 4.96 | 3.56–6.91 | 10.13 | 7.04–14.57 | 0.004 |
| Psychological comorbidities | |||||
| Anxiety in past 12 months | 14.1% | 6.7%–27.2% | 28.0% | 15.5%–45.0% | 0.115 |
| Depression in past 12 months | 16.5% | 8.4%–29.9% | 39.8% | 25.2%–56.5% | 0.020 |
| Insomnia in past 12 months | 29.6% | 18.6%–43.6% | 41.0% | 26.7%–57.0% | 0.264 |
| Taiwan (N=259) | |||||
| Mild CC (VAS≤4) (N=153) | Severe CC (VAS>4) (N=106) | P-value | |||
|
Mean SE |
95% LCL–95% UCL |
Mean SE |
95% LCL–95% UCL | ||
| HRQoL | |||||
| Physical Component Summary Score | 49.22 | 48.17–50.26 | 47.41 | 46.17–48.65 | 0.029 |
| Mental Component Summary Score | 42.73 | 41.50–43.96 | 41.80 | 40.34–43.26 | 0.341 |
| SF-6D Health Utilities Score | 0.66 | 0.65–0.68 | 0.65 | 0.63–0.66 | 0.061 |
| EQ-5D-5L Health Utilities Score | 0.83 | 0.81–0.85 | 0.80 | 0.77–0.82 | 0.103 |
| WPAI | |||||
| Absenteeism (N = 108/78) | 1.8% | 1.1%–3.2% | 5.5% | 2.9%–10.5% | 0.016 |
| Presenteeism (N = 109/79) | 23.8% | 20.1%–28.2% | 29.1% | 24.0%–35.3% | 0.129 |
| Total work productivity impairment (N = 108/78) | 25.4% | 21.6%–30.0% | 31.5% | 26.0%–38.1% | 0.097 |
| Total activity Impairment | 24.1% | 21.0%–27.7% | 32.7% | 27.7%–38.5% | 0.006 |
| HRU | |||||
| No. of HCP visits in past 6 months | 5.33 | 4.48–6.34 | 6.83 | 5.57–8.37 | 0.071 |
| Psychological comorbidities | |||||
| Anxiety in past 12 months | 9.4% | 5.7%–15.1% | 15.5% | 9.7%–23.7% | 0.134 |
| Depression in past 12 months | 8.8% | 5.0%–15.0% | 13.7% | 8.0%–22.3% | 0.242 |
| Insomnia in past 12 months | 44.8% | 36.8%–53.1% | 48.9% | 39.1%–58.7% | 0.537 |
CC, chronic cough; EQ-5D-5L, EuroQuality of life-5 Dimension 5 Level; HCP, healthcare professions; HRQoL, health-related quality of life; HRU, healthcare resource utilization; LCI, lower confidence interval; SE, standard error; SF-6D, Short-Form Six-Dimension; UCI, upper confidence interval; VAS, visual analog scale; WPAI, work productivity and activity impairment