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. 2022 Aug 3;121(17):3271–3285. doi: 10.1016/j.bpj.2022.07.023

Table 2.

Clot scenario descriptions with varying parameters

Scenario % fibrin in clot periphery redistributed (R) Contracted (C) (i.e., volume shrinkage) Uncontracted (U) Tightly packed periphery (T) Loosely packed periphery (L)
90RCT 90 X X
50RCT 50 X X
90RCL 90 X X
90RUL 90 X X
50RUL 50 X X
0RU 0 X NA NA

Fibrin redistribution on the clot periphery: 90% of total fibrin is in the periphery (90R)/50% of total fibrin is in periphery (50R)/clot is a homogeneous mixture of RBCs and fibrin, with 0% of fibrin in the periphery (0R). Volume shrinkage: contracted (C)/uncontracted (U). Fibrin structure: tight, pore size between fibers is 0.22 μm (T)/loose, pore size between fibers is 1.014 μm (L). All contracted clots have tightly packed core regions, and all uncontracted clots have loosely packed core regions. 0RU represents a clot where contraction is impaired; 90RCT corresponds to a fully contracted clot. NA, not available.