Cooperation between myosin and actin leads to network fragmentation. (a–c) Violin plots showing the number of domains in the actin density field obtained at a threshold concentration of 40 μM at different Arp2/3 concentrations (X axis). Myosin mole ratios are mentioned above each panel. (d–f) Violin plots showing actin concentration in high-density actin domains. Note that the domains are determined based on the mean concentration threshold, while the concentration plotted here is calculated based on actin concentration determined from filament data. Hence, the actin concentration in domains can be below the mean concentration threshold. (a–f) Plots also show median values (gray) and 25% and 75% quantiles as boxplots (black). Whiskers represent data ranges (yellow lines), and outlier data are plotted as yellow circles (mole ratio of myosin heads to actin = 0.1, Nsimulations = 6, mole ratio of myosin heads to actin = 0.05 and 0.01, Nsimulations = 5, data points = last 100 s, sampling frequency = 5 s). To see this figure in color, go online.