Figure 3.

Calcium-bridged interactions between PIP2 and POPC show strong negative curvature. Experienced curvature is plotted for lipids as monomers or as in complex. The additive model is shown in gray, and monomers are striped. Dimers are crosshatched. ${\text{Ca}}^{2+}$-mediated dimers are solid. The bottom panels are representative molecular configurations of each type (PIP2-PIP2, PIP2-${\text{Ca}}^{2+}$-PIP2, and PIP2-${\text{Ca}}^{2+}$-POPC). To see this figure in color, go online. Error bars represent one SEM.