Table 1.
Baseline characteristics by quartiles of premature ventricular complex frequency
| All | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P value | |
|---|---|---|---|---|---|---|
| No of individuals | 375 | 86 | 101 | 94 | 94 | |
| Range of PVCs/24 hours | 0–19,990 | 0–2.1 | 2.1–10.0 | 10.0–77.2 | 77.2–19,990 | |
| Age at baseline, years | 64.5 ± 5.9 | 62.0 ± 6.4 | 64.6 ± 5.8 | 65.2 ± 5.5 | 66.0 ± 5.0 | <.001 |
| Male sex (%) | 45.1 | 36.0 | 36.0 | 54.7 | 53.2 | .010 |
| Height, cm | 169.0 ± 9.4 | 168 ± 8.8 | 167.4 ± 9.9 | 169.4 ± 9.4 | 170.5 ± 9.1 | .100 |
| Weight kg | 77.3 ± 13.3 | 75.8 ± 13.2 | 76.5 ± 12.0 | 77.0 ± 12.8 | 79.7 ± 14.9 | .195 |
| BMI, kg/m2 | 27.0 ± 3.9 | 26.7 ± 3.9 | 27.3 ± 4.1 | 26.8 ± 3.8 | 27.3 ± 4.0 | .601 |
| Systolic blood pressure, mm Hg | 143.7 ± 18.5 | 141.7 ± 19.8 | 140.2 ± 15.4 | 144.5 ± 18.5 | 148.4 ± 19.6 | .011 |
| Blood pressure medication, (%) | 16.0 | 15.1 | 16.8 | 14.9 | 17.0 | .967 |
| Diabetes (%) | 9.3 | 11.7 | 9.9 | 9.2 | 10.6 | .903 |
| Prevalent CAD (%) | 1.1 | 2.3 | 0 | 1.1 | 1.1 | .497 |
| High physical activity† (%) | 25.2 | 19.8 | 22.2 | 31.6 | 26.9 | .343 |
| Low physical activity‡ (%) | 24.9 | 25.6 | 31.3 | 21.1 | 21.5 | .356 |
| Ever smoker (%) | 58.7 | 60.0 | 59.0 | 53.7 | 61.7 | .647 |
| Current smoker (%) | 22.7 | 20.9 | 31.0 | 16.8 | 21.3 | .129 |
| Alcohol, g/day, median (IQR) | 7.0 (1.3–14.3) | 6.1 (1.3–13.0) | 6.5 (0.9–14.1) | 7.0 (1.3–14.0) | 8.8 (2.8–17.7) | .407§ |
| HOMA-IR, median (IQR) | 2.1 (1.4–3.1) | 2.1 (1.3–3.2) | 2.2 (1.5–3.3) | 2.2 (1.6–3.2) | 1.7 (1.2–3.0) | .241§ |
| NT-proBNP, pg/mL, median (IQR) | 10.8 (1.7-32.7) | 3.7 (0.5-28.0) | 11.3 (1.8-32.1) | 13.4 (4.2-24.8) | 15.5 (4.1-62.9) | .004§ |
Continuous variables are reported as mean ± standard deviation except for alcohol use, HOMA-IR, and NT-proBNP, which are reported as median (IQR).
P values are calculated using χ2 test for binary variables or ANOVA for continuous variables.
BMI = body mass index; CAD = coronary artery disease (history of myocardial infarction or coronary artery bypass graft); HOMA-IR = homeostatic model assessment of insulin resistance; IQR = interquartile range; PAC = premature atrial complex; PVC = premature ventricular complex.
Upper quartile of physical activity score.
Lower quartile of physical activity score.
Variable is log-transformed prior to ANOVA testing owing to skewness in distribution.