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. 2022 May 16;3(4):344–350. doi: 10.1016/j.hroo.2022.05.008

Table 4.

Multivariable Cox regression models for atrial fibrillation, heart failure, and stroke by strata of premature ventricular complexes and premature atrial complexes

Low PVCs and PACs
High PVCs, low PACs
High PACs, low PVCs
High PVCs and PACs
HR (95% CI) Events/subjects HR (95% CI), P value Events/subjects HR (95% CI), P value Events/subjects HR (95% CI), P value Events/subjects
Atrial fibrillation ref 34/221 1.3 (0.7–2.5), .455 13/60 1.5 (0.8–2.7), .200 21/60 4.1 (2.4–6.8), <.001 21/34
Heart failure ref 10/221 2.1 (0.7–6.4), .196 5/60 1.0 (0.3–3.7), .998 4/60 4.3 (1.7–11.4), .003 9/34
Stroke ref 8/220 2.3 (0.7–7.5), .183 5/59 2.6 (0.9–7.5), .070 10/60 3.1 (1.0–9.7), .055 5/33

All models are weighted for the stratified sampling. Age was used as a time scale. Adjusted for sex, ever-smoking status, body mass index, and the use of blood pressure medication.

Low PVCs and PACs = quartiles 1–3 for PVCs and PACs; high PVCs and PACs = quartile 4 for PVCs and PACs.

CI = confidence interval; HR = hazard ratio; PAC = premature atrial complex; PVC = premature ventricular complex.