Table 2.
Clinical outcomes between study cohorts
| Outcomes | Low LDH (≤ 328) | High LDH (> 328) | P |
|---|---|---|---|
| MIMIC III | N = 1749 | N = 576 | |
| In-hospital mortality, n (%) | 27 (1.5%) | 51 (8.9%) | < 0.001 |
| 1-year mortality, n (%) | 131 (7.5%) | 107 (18.6%) | < 0.001 |
| Prolonged ventilation, n (%) | 222 (12.7) | 207 (35.9%) | < 0.001 |
| CRRT, n (%) | 86 (4.9%) | 77 (13.4%) | < 0.001 |
| ICU stay > 6 days, n (%) | 307 (17.6%) | 264 (45.8%) | < 0.001 |
| Hospital stay > 15 days, n (%) | 356 (20.4%) | 242 (42.0%) | < 0.001 |
| MIMIC IV | N = 1196 | N = 191 | P |
|---|---|---|---|
| In-hospital mortality, n (%) | 20 (1.7%) | 15 (7.8%) | < 0.001 |
| 1-year mortality, n (%) | 36 (3.0%) | 18 (9.4%) | < 0.001 |
| Prolonged ventilation, n (%) | 181 (15.1%) | 85 (44.5%) | < 0.001 |
| CRRT, n (%) | 67 (5.6%) | 35 (18.3%) | < 0.001 |
| ICU stay > 6 days, n (%) | 114 (9.5%) | 52 (27.2%) | < 0.001 |
| Hospital stay > 15 days, n (%) | 160 (13.4%) | 83 (43.5%) | < 0.001 |
MIMIC Medical Information Mart for Intensive Care, LDH lactate dehydrogenase, ICU intensive care units, CRRT continuous renal replacement therapy