Table 3.

Partial Spearman correlation coefficients between dietary scores and inflammatory and thrombotic biomarkers

Biomarker	DASH score		MD score		DII score		E-DII score
	ρ coefficient	p	ρ coefficient	p	ρ coefficient	p	ρ coefficient	p
C3, mg/dl	− 0.094	< .001	− 0.040	.114	0.070	.005	0.056	.026
CRP, ng/ml	− 0.059	.018	− 0.073	.004	0.077	.002	0.081	.001
IL-6, pg/ml	− 0.089	< .001	− 0.060	.016	0.082	.001	0.095	< .001
TNF-α, pg/ml	− 0.097	< .001	− 0.053	.035	0.076	.002	0.099	< .001
Adiponectin, ng/ml	0.029	.245	− 0.019	.45	− 0.013	.594	− 0.001	.96
Leptin, ng/ml	− 0.023	.364	− 0.027	.278	0.044	.08	0.042	.094
Resistin, ng/ml	− 0.025	.323	0.004	.883	0.062	.013	0.057	.023
PAI-1, ng/ml	− 0.030	.236	0.025	.327	0.009	.726	− 0.007	.777
WBC, 109/l	− 0.104	< .001	− 0.060	.016	0.102	< .001	0.072	.004
Neutrophils, 109/l	− 0.118	< .001	− 0.077	.002	0.125	< .001	0.096	< .001
Lymphocytes, 109/l	− 0.022	.383	− 0.014	.588	0.007	.792	0.002	.926
NLR	− 0.074	.003	− 0.040	.111	0.091	< .001	0.072	.004
Monocytes, 109/l	− 0.077	.002	− 0.048	.053	0.054	.029	0.033	.187
Eosinophils, 109/l	− 0.032	.194	− 0.010	.686	0.017	.498	0.005	.84
Basophils, 109/l	− 0.022	.388	0.001	.981	0.011	.645	0.018	.479

p value of < 0.05 was considered to be statistically significant. p values are highlighted in bold

Models adjusted for sex, age, education, use of anti-inflammatory medications, type 2 diabetes, CVD, cancer, never/former/current smoker, physical activity, BMI and total energy intake. Models which examine the E-DII score do not adjust for total energy intake. Values are presented as partial Spearman correlation coefficients between continuous dietary scores and inflammatory and thrombotic biomarkers among the Mitchelstown Cohort (n = 1862). Significant p highlighted. For the DASH and MD, lower scores represent poorer and higher scores represent better quality diet. For the DII and E-DII, higher scores are more pro-inflammatory and lower scores are anti-inflammatory

C3 complement component 3, CRP c-reactive protein, DASH Dietary Approaches to Stop Hypertension, DII Dietary Inflammatory Index, E-DII Energy-adjusted Dietary Inflammatory Index, IL-6 interleukin 6, MD Mediterranean Diet, TNF-α tumour necrosis factor-alpha, PAI-1 plasminogen activator inhibitor 1, WBC white blood cell count, NLR neutrophil-to-lymphocyte ratio