Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 10;12:15273. doi: 10.1038/s41598-022-19351-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Iba-1 and APOE immunostaining (A,B) (I-Iba-1, II-APOE, III-DAPI, IV-Brightfield (BF),V-Merged) was performed, microglial expressing APOE were higher in Mfrp^KI/KI mice retina compared with WT retina in all layers (C) (*p < 0.01) (D) in the subretina APOE positive microglia were significantly greater in Mfrp^KI/KI (***p < 0.001) (n = 3) observed under fluorescence microscope using a × 20 lens and particularly found in the GCL, IPL, INL, OPL and in the subretina (white arrows) (GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer plexiform layer, RPE retinal pigment epithelial cell layer).