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. 2022 Sep 10;12:15273. doi: 10.1038/s41598-022-19351-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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TMEM119 and CD68 immunostaining (A&B) (I-TMEM119-1, II-CD68, III-DAPI, IV-Brightfield (BF), V-Merged) was performed, microglial expressing TMEM119 were higher in WT mice retina compared with Mfrp^KI/KI. In subretinal region TMEM119 and CD68 positive microglia were particularly present in Mfrp^KI/KI which completely absent from WT (white arrows) (GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer plexiform layer, RPE retinal pigment epithelial cell layer).