Table 2.
Objective settings for optimization with the big model and each single-institution model.
| Institution | Organ | Objective | Volume | Dose | gEUD | Priority | Objective | Volume | Dose | Priority | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A | Rectum | Upper | 0% | 100% | Generate | CTV | Upper | 0% | 104% | Generate | |
| Line | Generate | Lower | 100% | 100% | Generate | ||||||
| Bladder | Upper | 0% | 100% | Generate | PTV | Upper | 0% | 104% | Generate | ||
| Line | Generate | Lower | 100% | 90% | Generate | ||||||
| B | Rectum wall | Line | Generate | PTV | Upper | 0% | 102% | 120 | |||
| Bladder wall | Line | Generated | Lower | 100% | 99% | 120 | |||||
| C | Rectum | Upper | 0% | 100% | 0 | PTV | Upper | 0% | 100% | 115 | |
| Upper gEUD | 69.2% | 9 | Generate | Lower | 100% | 93.0% | Generate | ||||
| Line | Generate | Lower | 97% | 96.0% | Generate | ||||||
| Bladder | Line | Generate | Lower | 95.50% | 98.0% | Generate | |||||
| Lower | 90% | 100.0% | Generate | ||||||||
| D | Rectum | Upper | 0% | 76.9% | 85 | CTV | Upper | 0% | 100.0% | Generate | |
| Line | Generate | Lower | 95% | 97% | Generate | ||||||
| Bladder | Upper | 0% | 79.5% | 75 | Lower | 100% | 94.9% | Generate | |||
| Line | Generate | PTV | Upper | 0% | 94.9% | Generate | |||||
| E | Rectum | Upper | 0% | 99% | Generate | CTV | Upper | 0% | 102.6% | Generate | |
| Upper gEUD | 76.9% | 10 | Generate | Lower | 100% | 99% | Generate | ||||
| Line | Generate | PTV | Upper | 0% | 103% | Generate | |||||
| Bladder | Line | Generate | Lower | 100% | 90% | Generate | |||||
| Lower | 96% | 96% | Generate |
gEUD Generalized equivalent uniform dose; CTV Clinical target volume; PTV Planning target volume.