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. 2022 Sep 10;13(9):783. doi: 10.1038/s41419-022-05224-7

Fig. 6. P130cas expression correlated with YAP as well as worse radio-therapy responses in human NSCLC samples.

Fig. 6

A Pan-cancer expression analysis illustrated the universal expression of P130cas in multiple malignant tumor types. B Kaplan–Meier analysis using the data from TCGA database showed a correlation with P130cas expression and NSCLC patient survival time. C GEPIA database analysis showed the correlation of mRNA levels between P130cas and YAP in NSCLC. D Representative images of immunohistochemistry staining of P130cas and YAP in the same NSCLC patients, scale bar: 50 μm. E Quantification data using Spearman’s rank correlation demonstrated a correlation between the expression of P130cas and different radiotherapy responses (PR/CR or PD/SD) after 4weeks (left panel) or 12 weeks (right panel). Quantification data are expressed as Mean ± SD of three independent experiments (t test. *P < 0.05, **P < 0.01, ***P < 0.001).