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. Author manuscript; available in PMC: 2022 Sep 11.
Published in final edited form as: Ann Oncol. 2021 Apr 20;32(7):839–853. doi: 10.1016/j.annonc.2021.03.207

Figure 1. Treatment algorithm for SCLC in patients with limited-stage disease (i.e. stage I-III SCLC eligible for curative treatment).

Figure 1.

Purple: general categories or stratification; red: surgery; dark green: radiotherapy; blue: systemic anticancer therapy; turquoise: combination of treatments or other systemic treatments; white: other aspects of management.

c, clinical; CRT, chemoradiotherapy; M, metastasis; MRI, magnetic resonance imaging; N, node; p, pathological; PCI, prophylactic cranial irradiation; PS, performance status; R, resection; SCLC, small-cell lung cancer; T, tumour.

a After extensive pathological mediastinal staging.

b The role of PCI is not well defined in patients with stage I-II SCLC, patients >70 years of age and frail patients. In these cases, shared decision making is recommended, including the option of brain MRI surveillance.