Table 2.

Summary of assay inclusivity.

Target	N differences in haplotype	N different haplotypes	Frequency	N haplotypes with impact∗	Frequency with impact†	Total %	% with impact
1	0	238	1,857,440	0	0	99.07%	0%
	1	235	17,139	0	0	0.91%	0.0000%
	2	42	339	9	21	0.018%	0.0011%
	3	10	10	7	7	0.0005%	0.0004%
	4	2	2	1	1	0.0001%	0.0001%
	5	1	1	0	0	0.0001%	0%
	6	1	1	1	1	0.0001%	0.0001%
	7	1	1	1	1	0.0001%	0.0001%
2	0	243	1,865,363	0	0	99.49%	0%
	1	227	9465	5	467	0.50%	0.0249%
	2	34	65	3	4	0.0035%	0.0002%
	3	4	4	3	3	0.0002%	0.0002%
	4	3	3	3	3	0.0002%	0.0002%
	5	3	3	3	3	0.0002%	0.0002%
	6	6	17	6	17	0.0009%	0.0009%
	7	6	9	6	9	0.0005%	0.0005%
	8	2	2	2	2	0.0001%	0.0001%
	9	2	2	2	2	0.0001%	0.0001%
combined	0	1	1,847,992	0	0	98.56%	0%
	1	365	26,367	0	0	1.41%	0%
	2	121	515	0	0	0.027%	0%
	3	16	18	0	0	0.0010%	0%
	4	5	5	0	0	0.0003%	0%
	5	4	4	0	0	0.0002%	0%
	6	7	18	0	0	0.0010%	0%
	7	6	7	0	0	0.0004%	0%
	8	3	5	0	0	0.0003%	0%
	9	2	2	0	0	0.0001%	0%

^∗Number of different sequence haplotypes in the database with the indicated number of differences and a predicted impact on assay performance.

^†Number of database entries with the indicated number of differences and a predicted impact on assay performance.