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. 2022 Sep 7;15:1245–1261. doi: 10.2147/JAA.S360381

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© 2022 Xiang et al.

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miR-93-5p mediated the effects of H19 on Orai1 expression, and the proliferation and migration rates of hBSMCs. In vitro cultured hBSMCs were transinfected with H19-specific siRNA with or without miR-93-5p mimic or inhibitor under stimulation with IL-13 (10 ng/mL). (A) Relative mRNA expression of Orai1 compared with control (without IL-13 and transfection). (B) Relative protein expression of Orai1 under different treatments, β-actin was used as internal control. (C) Proliferation rates of hBSMCs after 24 h and 48 h with different treatments as indicated. (D) Migration rates of hBSMCs under different treatments as indicated. *P<0.05; **P<0.01; ***P<0.001. n=3 for each experiment.

Abbreviation: ns, not significant.