Table 1.
Clinical and demographic information for patients with splanchnic vein thrombosis.
| Total | No composite event |
Composite event |
|
|---|---|---|---|
| Patients | 269 | 162 | 107 (40%) |
| Sex, n (%) | |||
| Male | 183 (68%) | 109 | 74 (40%) |
| Female | 86 (32%) | 53 | 33 (38%) |
| Age, median (IQR) | 61 (54–66) | 60 (54–65) | 62 (56–66) |
| Etiology of liver disease | |||
| Viral hepatitis | 73 (27%) | 48 | 25 (34%) |
| Alcoholic cirrhosis | 46 (17%) | 28 | 18 (39%) |
| NASH | 36 (13%) | 19 | 17 (47%) |
| Autoimmune | 13 (5%) | 9 | 4 (31%) |
| Multifactorial | 78 (29%) | 42 | 36 (46%) |
| Other or unknown | 23 (9%) | 16 | 7 (30%) |
| Clinical indices | |||
| Smoker | 66 (25%) | 39 | 27 (41%) |
| History of VTEa | 18 (7%) | 9 | 10 (56%) |
| Varicesa | 166 (62%) | 93 | 73 (44%) |
| Ascitesa | 155 (58%) | 92 | 63 (41%) |
| Encephalopathya | 63 (24%) | 38 | 25 (40%) |
| Tumor thrombus | 81 (30%) | 48 | 33 (41%) |
| Obstructive clota | 84 (32%) | 45 | 39 (46%) |
| Aspirin use | 26 (10%) | 14 | 12 (46%) |
| MELD, median (IQR) | 14 (10–19) | 14 (10–19) | 14 (11–19) |
| BMI, mean (SD) | 29.5 (6.7) | 29.9 (6.7) | 28.9 (6.8) |
| Location of thrombus | |||
| Portal vein | 210 (78%) | 130 | 80 (38%) |
| Superior mesenteric vein | 5 (2%) | 4 | 1 (20%) |
| Multiple splanchnic | 47 (17%) | 25 | 22 (47%) |
| veins | |||
| Other | 7 (3%) | 3 | 4 (57%) |
| Lab values, mean (SD) | |||
| Na | 136 (5) | 136 (5) | 137 (4) |
| Cr | 1.0 (0.7) | 1.1 (0.8) | 1.0 (0.6) |
| INR | 1.4 (0.7) | 1.5 (0.8) | 1.4 (0.3) |
| Platelet count | 112 (87) | 109 (65) | 117 (113) |
| Total bilirubin | 3.2 (5.8) | 3.8 (6.9) | 2.2 (3.1) |
| Hgb | 11.8 (2.5) | 11.8 (2.6) | 11.8 (2.4) |
a
As documented at time of diagnosis.